Cardarine (GW-501516) - The Endurance-Improving King

To begin with, it is important to clarify that Cardarine is often wrongly labeled as a SARM (Selective Androgen Receptors Modulator) by various supplement brands as a marketing ploy. In fact, this agent does not directly affect the function of androgen receptors in muscles and bones and has nothing in common with it.

Cardarine is actually a PPAR (peroxisome proliferator-activated receptor) Delta pathway activator, which is a transcription compound belonging to the PPAR receptors group. PPARδ aids in gene expression, mitochondrial development, insulin sensitivity, and beta-oxidation of fatty acids.  

It is interesting to note that there are almost no conclusive studies on the potential side effects of using Cardarine. It be considered a side effect-free compound, with only one study suggesting a slight acceleration in cancer cell development in rats using very high dosages (10x higher than recommended). On the other hand, some studies suggest that Cardarine may prevent cancer cell development. None side effects were observed in humans by far. 

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For athletes looking to improve their physical condition, Cardarine is a highly effective option. Studies have shown that it can increase physical capacity by up to 50-70%.
In addition, tests on mice have demonstrated an increase in running distance by up to 48.6%. Furthermore, Cardarine offers many benefits, including:
- the increase of "good" cholesterol (HDL) levels and reduction of "bad" cholesterol (LDL) levels
- prevention of fat cell development
- improvement of muscular endurance
- increase in thermogenesis, acceleration of lipolysis (the conversion of stored fat to energy)
- reduction of catabolism
- reduction of inflammation
- protection of the heart, liver, and blood vessels

Importantly, Cardarine will not block HPTA, reduce testosterone levels, increase estrogen levels, or have a hepatotoxic effect. It also does not require PCT. 

The recommended dosage of Cardarine is 10-20mg per day.

It's important to be aware that supplements can be contaminated with other substances. If you are taking cardarine, it's recommended that you have blood tests done during your cycle to ensure the product is not contaminated with any SARM/PH or AAS, which can cause harmful side effects. Always pay close attention to how your body and mind react during the cycle.