DECENTRALIZED MEDICINE #20: THE BIG TECH SPONSORED LIE OF THE MEANS SIBLINGS : LEPTIN/MELANIN/LIGHT

Tissue atrophy and inflammation in retina cells in the far periphery of the retina were most predictive of cognitive status, the study found.  This is where the iPRGCs of melanopsin are located. https://lakegenevanews.net/lifestyles/health-med-fit/alzheimers-first-signs-may-appear-in-your-eyes-study-finds/article_91986868-0e1a-5002-80d2-29bd618e20a9.html

Microglial cells declined by 80% in those with cognitive issues, the study found.  POMc is located in microglial cells.

RPE cells are located between photoreceptor cells and the choroid membrane, with the basal side connected to Bruch's membrane and tip microvilli connected to the outer segment of photoreceptor cells (Figure 1).

Damage to the structure and function of the retinal pigment epithelium leads to a variety of retinopathies, and there is currently no curative therapy for these disorders.  The reason for this belief is because modern medicine has no idea that renovating POMC internally by improving mitochondrial redox power and optimizing hemoglobin delvery is the key to RPE repair.  

Light in our environment plays the most dominent role in obesity. The slide below shows how badly the food gurus have missed the boat.

Control of food intake and energy metabolism relies upon a complex interplay between neural networks in the central nervous system and peripheral tissues. They key in understanding is how all 3 MSH molecules from POMC decrease appetite increase satiety while increasing energy expenditure. No diet does that. Exercise does not do those thrings in unison. Only sunlight does it. as thes lide below shows. More sun = less food consumed and higher basal metabnolic rate because sunlight increases T3 and T4 while lowering TSH.

Within the central nervous system, energy homeostasis is largely controlled by a fine balance between orexigenic and anorexigenic neuropeptides in the hypothalamic arcuate nucleus (ARC). Neuropeptide Y (NPY) and Agouti-related protein (AgRP) are coexpressed in neurons of the ARC and are potent orexigenic peptides, whereas proopiomelanocortin (POMC) precursor protein in the ARC is cleaved into potent anorexigenic α-melanocyte-stimulating hormone peptides. NPY/AgRP and POMC neurons in the ARC are considered “first-order” sensory neurons in the control of energy homeostasis (1) and receive, coordinate, and respond to changes in nutrient and hormonal fluctuations associated with changes in metabolic status. NPY acts on Y1 and Y5 receptors in the paraventricular nucleus of the hypothalamus to stimulate feeding, whereas acetylated α-melanocyte-stimulating hormone and AgRP peptides act as agonists and antagonists, respectively, at the melanocortin 4 receptor (MC4R). The POMC and AgRP interaction at the MC4R is collectively known as the melanocortin circuit. The critical importance of the melanocortin system in food intake and energy balance is highlighted by conditional gene ablation experiments. Ablation of POMC neurons in adulthood produced an increase in food intake and body weight and caused glucose intolerance, whereas ablation of AgRP resulted in rapid hypophagia, weight loss, and starvation = anorexia

Where the defect is on the retina and skin determines whether you get obesity or anorexia. We see this in drug addicts, alcoholics, and we see it in anorexics who live inside behind glass and infront of sceens. Both conditions, however, are associated with altered signaling in the leptin melanocortin pathways.

Why did obesity really happen dramatically after 1874 when the power grid was begun? LIGHT. It brought us INSIDE where the PROBLEM was.

When we started plugging in to the AC power all hell broke loose and this is where MOST chronic disease epidemics began. HARD STOP

Governments allowed NGOs like Gates and dermatologists began to advocate blocking the sun while putting screens in front of millions of humans from 1947 on. In 2009 Barry Obama and Biden changed FCC broadcast transmission from analog to digital and this brought LCD and plasma screens. Now LCD screen make up 99% of screens. All screens default setting out of a FACTORY ARE SET to blue frequencies. THIS MAKES YOU MORE COMPLIANT TO GOVERNMENT PROGRAMMING. The evolutionary time line of light makes this abundantly clear. Food gurus like the MEANS SIBLINGS are like propaganda wings of the Federal government who are now weaponizing MKULTRA programming at GLOBAL SCALE. They are paid by a16z who is a Silicon Valley investment group who supports Big Tech where all blue light begins.

THIS WAS THE GOAL OF MKULTRA ----> https://www.youtube.com/watch?v=SiBFtwbyv44

In 2007 Barry Obama said we are also going to remove incandescents which contain some UV and IR. the government knew what they were doing. They knew it make you more susceptible to things coming from Wuhan. They told us that it was to lower energy bills. That was a PR bullshit story that the media sold and then the food gurus were weaponized like legacy media reporters to repeat the liwe so you'd all believe it. AND 99% of you have.

They did it to lower our dopamine levels to make us more responsive to the political moves. This also lowered out melatonin levels simultaneously and this is why all kids now get Rx for melatonin from pediatricians who are complicit in the chronic disease epidemics. When dopamine and melatonin drops SO DOES POMC TRANSLATION. This means melanin never gets made properly. THAT IS WHERE YOUR DISEASE EPIDEMICS COME FROM.

Mental disease, drug addiction and obesity all come from obstruction of this pathway by modern lighting. LOOK AT THE PICK ABOVE. YOU ARE BEING LIED TO IN A BIG WAY by the NGO and Government partners in BigHarma and Big Tech that both sit at the CANTILLON EFFECT. Calley and CASEY MEANS ARE PAID BY THESE PEOPLE and this is why both of them have companies that use WBAN technology which MAKES YOU SICK. They got this idea from the Wojcicki sisters of YT and 23andme and YT and Google's Sergei Brin. See this here to show the PROOF -----> https://threadreaderapp.com/thread/1826512218088722575.htmlXIA 

THE DRUG ADDICT STORY BELOW LINKS TO WHY SOME GET ANOREXIA.

SUMMARY

In the leptin melanocortin system of the retinohypothalmic tracts in the eye the, hormones of the “fed state” such as leptin and insulin, are released in the bloodstream by adipocytes and by the β-cells of the pancreas, respectively, cross the blood-brain barrier to bind to leptin and insulin receptors on the surface of pro-opiomelanocortin (POMC) neurons to promote processing of POMC to the mature hormone α-melanocyte-stimulating hormone (α-MSH), which signals to decrease energy intake.

The three MSH molecules from proopiomelanocortin (POMC) decrease appetite, increase satiety, and increase energy expenditure: 

• Alpha-melanocyte stimulating hormone (α-MSH)

  A POMC-derived neuropeptide that binds to melanocortin-4 receptor (MC4R) in the brain to suppress appetite and increase energy expenditure 

• Melanocortin-4 receptor (MC4R)

  A receptor expressed by neurons in the paraventricular nucleus (PVN) that suppresses food intake when bound to α-MSH 

• POMC neurons

  Neurons in the hypothalamus that produce α-MSH and other peptides that act on MC4R-expressing cells 

Leptin and serotonin are signals that promote POMC neuron action, which leads to the production and release of α-MSH. In contrast, ghrelin is an orexigenic hormone that activates AgRP neurons, which antagonize MC4R signaling and increase food intake. 

Mutations in the POMC gene have been linked to severe childhood obesity. 

STOP LETTING THEM LIE TO YOU.

IT ALL BEGINS WITH LIGHT

CITES

Zarbin M. (2016). Cell-Based Therapy for Degenerative Retinal Disease. Trends Mol. Med.22 (2), 115–134. 10.1016/j.molmed.2015.12.007

Tian X., Cui Z., Liu S., Zhou J., Cui R. (2021). Melanosome Transport and Regulation in Development and Disease. Pharmacol. Ther. 219, 107707. 10.1016/j.pharmthera.2020.107707

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