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GPLD1 Production

A little-studied liver protein may be responsible for the well-known benefits of exercise on the aging brain, according to a new study in mice by scientists.

The findings could lead to new therapies to confer the neuroprotective effects of physical activity on people who are unable to exercise due to physical limitations.  

Exercise is one of the best-studied and most powerful ways of protecting the brain from age-related cognitive decline and has been shown to improve cognition in individuals at risk of neurodegenerative disease.

But many older adults are not able to exercise regularly due to physical limitations or disabilities, and researchers have long searched for therapies that could confer some of the same neurological benefits in people with low physical activity levels.

The new study, published July 9, 2020, in Science, showed that after mice exercise, their livers secrete a protein called Gpld1 into the blood. Levels of this protein in the blood correspond to improved cognitive function in aged mice, and a collaboration with the UCSF Memory and Aging Center found that the enzyme is also elevated in the blood of elderly humans who exercise regularly. But the researchers showed that simply increasing the amount of Gpld1 produced by the mouse liver could confer many of the same brain benefits as regular exercise.

This increases the production of GPLD1 in your liver and then it enters the blood stream to circulate throughout your body for help produce those beneficial effects. 

GPLD1 Production

Comments

of course ?

2 or 3 times a day

pseudonym

This one is so good

pseudonym

Just what my aging brain needed. Thank you.

How often should we play this? Thank you.

Jamie Anderson

Thank you so much!!!

Thank you, Sapien. 🙏

Clara Magdalena

This is really beautiful! Thank you Sapien!

AlKiMisT1111-aka-KimK

Wow I could feel the effects of this right away . I feel sharper in the brain , better mood . My skin looks better and my hair is softer . I also felt a little hypoglycemic which indicates it lowers blood sugar , enhances metabolism . All after only 1 and a half listens.

Moritz Alexander

Article about it https://www.npr.org/sections/health-shots/2020/07/09/889467347/an-enzyme-that-increases-with-exercise-can-improve-memory-in-mice-and-maybe-peop?t=1595787494475

Moritz Alexander

Can younger, more active people still listen to this as a preventative? Thanks!

Awesome... Gonna be playing this around my mom! Thank you sapien

I wish I could get my dad to listen to this. Gonna have to play this on the sly somehow lol


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