Ayari pauses to inquire if Rastus still remembers the days they lived in the reality they called home. He explains how Despond leaves a universe once it begins to erode and collapse to a new universe. His appearance disrupts the fabric of reality and brings destruction, but Despond at least lives another day.
Despond realizes if a universe can collapse due to time, ultimately he will to. That's what sparks his fascination with producing offspring of his own. The initial wave of three children are the progenitors of dragons...
Note: This is the only clear appearance we'll ever see of Despond in his original, true form. Even then, once colored, it will be VERY obscured. Despond is meant to be a terrible, inconceivable beast and drawing him in full would never do him justice...