Instagram Q & A 10/8/2024

Q: Ways to handle carbs better

A: Eat every meal outside in direct sunlight. Red light significantly lowers blood glucose levels. There was a recent paper that came out showing it reduced maximum glucose spikes after a meal pretty significantly. This was only using RLT panels as well. The sun is 50% red and near infrared light. So you don't even need to go out and buy a device to get those benefits in my opinion.

UV light itself also has a strong impact on BG. Honestly, not even worth taking supplements if you're not doing the basics.

Resistant starch before meals (green banana flour is my favorite) also works well and it's not expensive.

Q: Do you think there's anything worth looking into for muscle dystrophy

A: I think so. Mechano growth factor in particular has been shown to stimulate dystrophin. Same with beta glucans.

MGF itself also increases progenitor And mesenchymal stem cells, which also further increase the expression of dystrophin (which is the protein that's the body doesn't produce enough of with DMD). Then there's some rodent models with urolothin A showing it improves muscle function in mouse models of DMD. It also increases the regeneration of muscle stem cells. Also think the bio-regulator peptides for muscle (gotarix) and pinealon could be helpful. Pinealon is a brain bio-regulator but there's some studies showing it boosts irisin which has been studied as a therapeutic target in DMD for improving muscle strength. Some mitochondrial peptides maybe. I actually think there's lots of things!

Q: Low hanging fruit for energy production (supplements)

A: B-complex (preferably mine because they're formulated to perfection lol) vitamins (no multi, need to be concentrated B's) and Mitolife Shilajit. Everyone's unique, but I tend to think virtually everyone can benefit from those two supplements at varying doses (1-2 capsules of my B-complex, maybe 2 on days you sweat a lot) and 3-5 tablets of mitolife Shilajit (you can also find that in the bio under the mitolife tab). These will continue to be core recommendations. Primarily because (like you asked) they will help with energy production. But mainly because they're replacing lost trace minerals as well as water soluble vitamins which get used up fast when you exercise, are stressed and or sweat a bunch. Hard to beat a little magnesium with those 2 as well.

Q: More disease or better diagnosis?

A: It can be both sometimes. The only people who deny that are idiots with no skin in the game. They just pontificate over statics. They don't actually treat patients. Talk to most forthcoming doctors and pathologists - they're the ones seeing the chronic disease epidemic in their clinics and offices. Any doctor who's practiced medicine for 30-40 + years will tell you they are seeing more patients come in (especially young people)

with things like early onset dementia, neurological disorders, autoimmune disorders etc. you don't need complex diagnostics to believe somethings off when you suddenly have a massive influx of patients (especially young people) presenting with rare symptoms. This is a sorry excuse for nitwit social media scientists who don't understand complex environmental etiology of disease. Its a way for them to side step the problem because they don't understand it.

Nor do they want to give ammunition to the grifters. Self-preservation to avoid looking stupid. They're the same people who tell you we're destroying the environment with chemicals but deny any plausibility of harm in biological systems lol. Fools

Q: Sauna use benefits - spot on or inflated?

A: Overrated but not useless. Someone else asked a question regarding sauna and recovery so l'll answer that here - the reason ice baths and saunas do have some benefit is because they're STRESSORS. Not because they promote recovery. If anything they do the opposite. I remember the first time I did a contrast (ice bath + sauna) back and forth (Ithink was back in Highschool), I got extremely sick the following morning. Felt absolutely horrible most of the day immediately after as well. It's a stressor on the body. That's also why it's beneficial (when dosed appropriately and with other stressors like exercise considered). I think sauna is a more intense stressor because you'll lose minerals and get dehydrated. So rehydrating after is important. Don't use it everyday. If you're already training multiple times a week, forget it entirely

Q: Can eating organs every day cause vitamin toxicity?

A: Sure can. No point in eating them everyday.

Try once a week. And no, your ancestors definitely didn't eat organs every single day. They ate them when they could get their hands on them. Food availability = constant variability and flux within the diet. Daily, weekly and month-to-month

Q: You talked about Bemetil (metaprot) awhile ago are you still a fan/new insights?

A: Yes. I take it in the summer sometimes.

Especially if I'm going to be training outside or just out in the heat all day. It's an actoprotector/synthetic adaptogen, so I've also heard some people claim it helps with thermoregulation in cold environments as well. Most of the published research on it is for heat acclimation but I believe it could work both ways. Similar to some of the benefits rhodiola has for cold weather adaptation. Something else to consider - the byproduct of ramping up certain components of cellular metabolism and energy production can actually CAUSE you to overheat faster and expend more energy. So a lot of 'performance' supplements are likely something you want to avoid in the summer. Metaprot/ bemitil enhances performance but without additional oxygen consumption or heat production. Really important to keep in mind

Q: Ice baths or cold therapy totally useless?

A: Temperature I causes alterations in gene expression patterns associated with metabolism, circadian rhythms, and immune responses from seasonal changes (temperature-sensitive transcription factors).

Anyone telling you that tempature isn't a useful lever that you can pull for health related benefits is retarded. That doesn't mean you NEED to do ice baths lol. But yea. In general a lot of people ignore thermobiology. It impacts DNA methylation and histone acetylation and determines how organisms adapt to temperature changes. That used to be really important (before we lived in air conditioned bubbles) because it allowed for a flexible response to environmental stressors. That inate plasticity is part of surival. It's what enabled organisms to optimize their physiological functions in response to the seasonal variations in temperature. That directly influences things like their fitness, reproduction, and survival strategies within their ecological niches. Tempature (just like light) is another environmental cue. It's part of the reason why you need to be out and about in the winter and summer

Q: Ray peat thoughts on muscle meat and balancing with glycine?

A: Yup. Important to balance methionine from muscle meat. I get about 10g of glycine daily from various sources and then supplement a few grams as well. Low calorie jello has lots of glycine. So does broth and collagen.

Q: Layne says collagen is useless. Thoughts?

A: Layne, like many of the 'controlled trial' nitwits is a pseudo intellectual who regularly talks about things he doesn't understand. He makes false comparisons like whey protein vs collagen and its amino acid content) in order to dismiss it. It's a strawman. You're not taking collagen for the proline and glycine (necessarily, although those do have some seperate benefits as well). The actual idea behind collagen peptides is the very same idea behind a lot of the research Vladimir Khavinson did with short chain peptide bio-regulators (which has a long, extensive 40 year history of clinical and experimental investigation).

Short chain peptides work via single transduction pathways. Collagen peptides can bind to specific receptors on cell surfaces, like integrins.That interaction activates intracellular signaling pathways (e.g MAPK/ERK pathway as one example) which promotes cell proliferation and tissue specific benefits. Physionic did a video on this believe. Was nice actually seeing a larger 'science' based account acknowledge some of these mechanism as they're often ignored.