Oh, you know this case was right up Jane's alley. He's going to be talking about this for as long as he lives. Lol.
So, Jane gets a call from a woman who claims she's heard he was the best detective in California and she needed him to solve her murder. He and Lisbon get in a helicopter and head down to a biolab of sorts. When they get inside, they are greeted by some other agents who are already on site and make it clear that they are in charge.
We finally get inside and find one of the employees is quarantined in a room within a room. When she arrived to work that morning, she found a vial of the disease she works with broken in the room she's in. Only about six people have authorization to be in the room and it's got a retinal scanner, so it should be easy to narrow it down. The guys who work there are insisting she just made a mistake and is refusing to admit it, but the dying lady is adamant that someone broke this vial to murder her. We also find out that there is an antidote, but it has to be taken before exposure to the virus.
While we're talking to the six or so people who have access to the room, Jane is busy being Jane about it and finds out that the dying woman and her husband (who both have access) have both been having affairs, but they both insist they are in an open marriage and this isn't relevant to what's going on.
It's going to take some time for the room to decontaminant and while he's killing time, Jane is snooping around and playing with stuff, as he is wont to do. He tests out the eye scanner and the door slides open for him. Once we track down the security guy we find out that there was a bug (or something) in the system and they've been without security for, like, two months. So it turns out, everyone has access to the room so our suspect list just became everyone who's been in the building.
We also find out that one of the original six people who were suspects, changed her name after she got out of her marriage and had a restraining order put on her by her ex husband. And she's in love with the dead lady's husband. Jane hypnotizes her into telling him the truth, how would you get out of this building if you didn't want to use the front door. She tells him and he tells her to run away, which she does.
Then we find another open vial of the bacteria on a table. Which means, we've all been exposed and everyone in the building is going to be dead in the next 2-6 hours. Lisbon begs Jane to tell her that this is a trick of his, but he claims it's not. Everyone makes phone calls to their loved ones as they prepare to die. Lisbon calls Cho and gives him some instructions about calling her family. When she hangs up, Jane says he wanted to talk to him. Before he calls back he tells Lisbon that if they were going to die, he'd call her. And she realizes it is a Jane plan.
He explains that whoever broke the original vial must have taken the antidote before doing so, so they have immunity from this one. And after we're all dead, the army is going to drop bombs on the building insuring the virus never escapes. However, the one person who already has immunity is going to try to escape. He calls Cho and tells him and Rigsby to head the place the hypnotized girl told him about. And they roll up and arrest the guy who escaped.
Turns out, he'd been selling bits of the virus on the black market, but with the head guys there to do inventory, he needed a scapegoat for the missing bits. And he picked this lady because he was sure they would assume she'd made a mistake but refused to admit it. And that is exactly what happened.
Oh, and we get to watch Lisbon punch Jane is the face, which was fun.