Kidney Restorer (Premium Field)

After reading about the disadvantages of pluripotent stem cells. I decided to create a field to differentiate them and target them to a specific organs( See Maximize Self Healing Potential). Scientist recently did the same to complete regenerate a kidney. This is quoted from an article released yesterday 

"Over 93,000 people in the US are in need of a kidney transplant. Our kidneys are delicate organs that can be damaged by a poor diet, overuse of alcohol or anti-inflammatory drugs, and high blood pressure, among other factors. They’re also hugely complex; each kidney contains around a million nephrons, intricate filters that let fluid and waste products through while retaining blood cells, proteins, and minerals.

Though a fully-functioning artificial kidney is years away at best, scientists are making incremental progress in replicating these vital organs. A team from Kumamoto University in Japan has just succeeded in recreating an often-overlooked yet integral piece of the kidneys: a connective tissue called the stroma.

In their paper, published yesterday in Nature Communications, the team describes how they used pluripotent stem cells from mice to create stromal progenitors, one of three key cell types that end up developing into functioning kidneys, each playing an essential role in the organ’s function. Stromal progenitors develop into stroma, the tissue that surrounds nephrons and ureteric ducts.

The team noted that although other studies have been able to create nephrons and ureteric ducts from stem cells, these didn’t fully function as they would in real kidneys due to the absence of stromal cells, which are crucial for cell signaling. The team took embryonic stem cells from mice and induced these to differentiate into kidney-specific stromal cells, using a cocktail of chemicals meant to mimic those that would occur in vivo.

When they combined the stromal cells with nephron and ureteric bud cells (which they also created from stem cells), the result was a “kidney-like 3D tissue, consisting of extensively branched tubules and several other kidney-specific structures.”

According to the researchers, this is the most complex kidney structure that’s been generated from scratch in a lab. Though this study was done in mice, the team noted that it has already created the first two kidney components—nephron progenitors and ureteric buds—from human induced pluripotent stem cells (iPSCs). If they’re able to also create stromal cells from iPSCs, they said, “a similarly complex human kidney should be achievable.”"

There idea is to use these cells to grow a new kidney. And then transplant that into the body. My idea is to use this process to restore and regenerate our existing kidneys. And that is exactly what this field aims to do! By differentiating each cell it will go beyond previous kidney restoring fields by restoring cells that previous fields has no effect on. Regular stem cells can only form into certain cells and are therefore limited. These cells will differentiate into every component of the kidney. Overtime giving you a brand new, "factory fresh" kidney. 1-2 times a day. Safe to Loop.