Virginia Preminger was a corporate spy attempting to steal a prototype cryogenic weapon when she first encountered Amazon Arrow and Dartgirl in the late 1960's. Unfortunately, Virginia's attempt to use the weapon backfired and her body was bathed in a freezing compound that permanently bonded with her cells. Virginia miraculously survived, but she cannot live for long in temperatures higher than fifty degrees below zero. Driven mad by her experience and forced to spend her existence inside of an environmental containment suit, Virginia now aspires to terraform the entire planet to create a subzero world for her to rule. The physiological changes to her cellular structure have also halted her aging process, preserving her youth (as well as her hatred for Amazon Arrow and Dartgirl) perhaps forever.
Virginia blames Dartgirl for her condition and she is looking forward to putting the Amazon Teen Angel on ice once and for all. Will Mistress Freeze succeed? Stay tuned! Same Dart-time! Same Dart-channel!