Mushroom chemistry talk
Added 2023-12-18 03:07:58 +0000 UTCPlease enjoy an hour long talk where I discuss different fungal natural products. Note: during the Q&A I estimate the global consumption of GMP psilocybin to be a couple of grams, that's almost certainly too conservative, but I would imagine it's less than fifty grams. Q&A and much more coming out this week!
Love,
Hamilton
Comments
I think She’s asking if he sees a future for bioreactor produced psilocybin, and he said it is possible
Josh Lis
2024-08-24 14:09:41 +0000 UTCYes I’ve seen that too, a shame really
Max van Oldeniel
2024-03-09 14:42:53 +0000 UTCMuch more than that is actually produced, but I'm talking about the sum quantity of GMP psilocybin consumed in clinical and preclinical research by humans to date, can't be much more than 50 grams.
Hamilton Morris
2024-01-26 20:17:16 +0000 UTCI don't understand....only a couple grams of GMP psilocybin? I'd have guessed a couple orders of magnitude more - or is there a special category of GMP? (good or green manufacturing processes? Isn't that what it means, Hamilton?) Is that nice GMP route to MDMA starting from benzo[1,2]dioxide in use? I suppose it should be in the DEA production quota, although they don't mention the synthetic details.... Hmmm...looks like the DEA aggregate production quota for MDMA for 2024 is 12 kilograms, which is more than a little bit... it's a start! Psilocybin and psilocin clock in at 20 and 24 kg respectfully, so there ya go! https://www.federalregister.gov/documents/2024/01/03/2023-28962/established-aggregate-production-quotas-for-schedule-i-and-ii-controlled-substances-and-assessment#:~:text=The%202024%20aggregate%20production%20quotas,to%20provide%20for%20the%20estimated. Thank you kindly for the talk everyone, interesting stuff!
Steven
2024-01-06 20:39:06 +0000 UTCGreat talk, is that an unusual number of shirtless dudes for a talk like this?
Tom Suazo
2024-01-05 17:04:31 +0000 UTCThank you Hamilton!
Evan Cohen
2024-01-02 21:08:23 +0000 UTC9
Jamie Howell
2023-12-28 01:20:59 +0000 UTCA
Jamie Howell
2023-12-28 01:20:41 +0000 UTC,2
Jamie Howell
2023-12-28 01:18:49 +0000 UTCAquatic chemistry hype woohoo💖🙌
Lightfaeee
2023-12-25 12:51:43 +0000 UTC1. straighten spine 2. tighten abs 3. shoulders back 4. head high (lulz) 5. ??? 6. PROFIT my nagging fingers shall know no rest until ppl I see on the internet fix their postures
Honey-el
2023-12-23 14:50:52 +0000 UTCI had somehow completely missed Alexander Sherwoods paper "Structure Elucidation and Spectroscopic Analysis of Chromophores of Chromophores Producedby Oxidative Psilocin Dimerization" I genuinely thought this was still a complete mystery.
jacob smith
2023-12-21 00:32:31 +0000 UTCThank you!
slunkd
2023-12-21 00:28:20 +0000 UTChttps://citeseerx.ist.psu.edu/document?repid=rep1&type=pdf&doi=9b0d15c9d6fc9db32b8ca0d6de18d4956b47180f
jacob smith
2023-12-21 00:27:11 +0000 UTCI am confused by the third question. She seems to state that the current method of production for therapeutic use is through GMO ecoli, but then she asks if we will be able to use bacteria in the future, and then Hamilton states that none of the three companies in phase 3 are using GMO bacteria to produce psilocybin. Can someone help me understand what she was asking?
Cheminterested
2023-12-19 18:42:21 +0000 UTCHas patreon removed the community chat section? There used to be a section under Hamilton's page with community conversations but it seems to be gone now.
Cheminterested
2023-12-19 18:30:40 +0000 UTCGreat talk. You are a very patient person for responding to the first question with such a good attitude. Hard for me not to roll my eyes so hard they fall out of head. I'm glad you are the person out there as the embassador of psychedelic science in the world
Cheminterested
2023-12-19 18:23:18 +0000 UTCHi Hamilton! Are you able to share the full “Biotransformation of tryptamine” paper? My short and probably poor googling is yielding only the abstract. Additionally, what is your opinion on the reliability/truth of the research?
slunkd
2023-12-19 03:33:43 +0000 UTCAnd I absolutely don't want to sound like I am not absolutely spoiled to live in a day and age where we can hear these talks and constantly build on the knowledge surrounding these organisms and thier compounds
Austin T.
2023-12-18 22:29:22 +0000 UTCGot ya, ya I feel alot of people are very recently interested in these topics and have not been horribly obsessed since a young age like others 🤣. When Hamilton mentions priceless commentary on topics like difficulty of synthesis of psilocybe compounds vs the also extremely difficult extraction, I find that beyond entertaining and awesome to listen to. Then he goes on to other amazing material like Gartz' work among other very niche and infinetly fascinating dialogoue. What gets me a little irritated every now again is when his beautiful work and pristine points of information get met with repetative questions along the lines of "natural vs synthetic" or other questions that are seemingly up to the individual to come to thier own conclusion with before taking his question time. I think the natural sources have a real magic about them but the questions regarded all that get asked at some goofy times. The questions are important as can be as far as I can tell and I am thankful you just wanted to talk Andrea🙏 much love, I am always open to talk. And much love to Hamilton for continously kicking ass and spreading the good info and opening up a full spectrum of dialogue!
Austin T.
2023-12-18 22:18:39 +0000 UTCOh yeah, absolutely agree. Sorry my comment may have souded a little harsh and I didn't mean for it to be harsh or rude.
Austin T.
2023-12-18 19:40:08 +0000 UTCamazing lecture hamilton thank you
Jean-Luc Gannon
2023-12-18 12:53:29 +0000 UTCfirst guys question 🤣🤣🤣
Jean-Luc Gannon
2023-12-18 12:52:50 +0000 UTCYour patience is awesome man, I am glad you put up with the "simpler" questions. Your question answering is definetly enlightening for the masses and totally entertaining. Thanks a ton, hopefully we can see more people advancing Gartz's work among many other topics your brought up. Thanks again🙏🙏🙏
Austin T.
2023-12-18 06:00:54 +0000 UTCI love getting a patreon notification for new content from Hamilton while I'm rewatching an episode of Pharmacopeia at that very moment
Josh Galloway
2023-12-18 05:30:21 +0000 UTCThis is why I’m a patreon member. No one else is sharing information like this at such an in-depth yet conversational level. Keep it up Hamilton! Soon you’ll have a spot on the MT. Rushmore of psychedelic history!
Tatum Scott
2023-12-18 03:44:12 +0000 UTCHey Hamilton thanks for going to central PA ❤️
Devan Ghai
2023-12-18 03:23:09 +0000 UTCThank you for editing the pictures in for better visibility
Leonard
2023-12-18 03:14:07 +0000 UTC
