Instagram Q&A 12/4/24

Q: Have you seen anyone reverse arthritis

A: Arthritis is generally one of the easiest inflammatory conditions to resolve via gut associated lymphoid/gut immuned mediated interventions. Fungal protocol (or some type of microbiome reset) improve tone/homeostasis and talk between adaptive/innate immunity. Spore based probiotics (just thrive, it's in the bio with a code) paraprobiotics (Holoimmune from HealthyGut), and pro-resolving mediators to help deal with the residuals. In the context of arthritis, the damaged tissue that SPMs clear is the inflammatory debris or exudate. Thats going to be dead cells, inflammatory cytokines, and other byproducts of the inflammatory response. So these need to be managed along with restoring immune tolerance to self-antigens. The residual damage from arthritis, particularly in the chronic cases, will lead to conditions like synovitis (inflammation of the joint lining) and cartilage degradation.SPM's promote clearing debris and enhancing the healing process.

Urolithin A can also be helpful for this. Also worth mentioning that none of this will be possible if you keep eating like shit and living an unhealthy lifestyle though

Q: Any peptide recommendations that would be renal protective/ rehabilitative?

A: pielotax (the kidney bio regulator)

Possibly GHK and BPC as well. I've seen a lot of really amazing results with cartalax and TB4 in particular for people with kidney issues. Also, red light therapy is amazing for kidney disease and other pathologies. In fact, that's probably one of the primary organs (aside from the brain) where it appears photobiomodulation (aka red light therapy) appears to have the most benefit. There's some good papers on this. I would look into kne if the higher intensity panels from

Gembared. Can be used directly on the kidneys. Even better if you lay on it.

Putting some weight and pressing the device into the skin will allow for better penetration. Molecular hydrogen inhilation has also been shown to be renal protective.

Q: What would you recommend for treating osteoarthritis in elderly people?

A: Carbon dioxide bathing (make the investment and buy the BodyStream suit if you're dealing with someone that's elderly tbh. Particularly women since they have the most issues with this. It'll work a lot better), magnetico sleep pad (the strongest 20 guass pad), PEMF therapy (done intermittently for symptoms flair management), SPM'S, balanced diet with lots of good healthy fats, particularly fatty fish, spore based probiotics, magnesium, high dose vitamin K (mitolife), lots of sunlight

Q: Any general thoughts on meditation? Thanks

A: It's useful but it's ultimately a fragmented practice if you're unable to integrated the skills gained from meditation into daily life. Technically, everything you do can and should be a meditation honestly. At least if you’re look at meditation through the lens of acquiring more unbroken focus and attention. I actually like transcendental style meditations and 'future envisioning' a little more, because I think the mood-elevating components are more signicant for the benefits conferred to health and immunity (le psycho-neuro-immunology context). But if you can be more actively engaged in legitimately living your life (finding passions and hobbies where being present and intentful come naturally, or even trying to apply some of that

'presentness' to things you don't enjoy, you'll be effectively practicing traditional focus oriented meditation

Q: Thoughts on benefits of hydrogen peroxide

A: Hydrogen peroxide acts as an oxygen donor, so it will promote oxidation, which can be beneficial for eliminating pathogens. The same is true for ozone and that's why it's often used for chronic Lyme. However, excessive oxidation in the body can also occur if carbon dioxide (levels are insufficient. hydrogen peroxide is a byproduct of oxidative stress, and many individuals already produce it in excess. So It's contextual. I would say combining hyperbaric, ozone, hydrogen peri oxide and other oxidative therapies with carbon dioxide bathing (prior) and molecular hydrogen (prior, during or after) can increase benefits and minimize downsides a lot. Using hydrogen peroxide is also done best with like red light therapy and eating enough carbs to also help boost C02 levels as well, so you're enhancing the body's ability to utilize oxygen effectively.

Q: Going from low UV area to high UV area. Any recommendations to get the benefits and not burn

A: Just gotta build up really slowly. Start by gradually accumulating the most exposure in the first 1-2 hours and last 1-2 hours when the sun is more red and infrared light. That will also precondition the skin to prevent burning when you're out in stronger UV light during the middle of the day. Just micro-dose higher UV mid day infusion for

10-15min at a time, 1-2x a day. Then build up to maybe an hour total. That's usually enough for most in 5-6 or more UV index. If you're super low latitude (like in South America) the UV will climb really fast, even in the first hour or two of the day. So if you're that low, you'll need to build up slowly even with morning and evening exposure since the drop off in the evening) and time to peak UV (in the morning) is a lot steeper.id also check out the internal sunscreen article on patreon for a full list of things you can supplement with to prevent burning.

Q: Does Shilajit actually raise testosterone

A: I've complied enough acnedotal case reports (at least over 300) demonstrating that it likely does.

Meaning someone took Shilajit (and no other supplements and made no significant lifestyle modifications) and increased testosterone by an average of at least 200 ng/dl. This is what I’ve seen, and I’ve been compiling these findings for about 5 years now. I don't think this is particularly difficult to understand though Shilajit doesn't have any magic benefits outside of the fact that's it's supplying more trace minerals and phyto nutrients that many aren't getting enough of in their diet. When you improve general health, you'll see

improvements in testosterone as well. This is why I recommend Shilajit as a staple supplement for all. Not because it increases testosterone, but because it's a general health tonic with a variety of well established. adaptogenic benefits. Many will point to the lack of research on Shilajit and testosterone, but this misses the point of taking it entirely. As I've mentioned, mitolife panacea is the only brand I'd recommend though. Most of not all are contaminated with mycotoxins and heavy metals

Q: Thoughts on RFK's plans

A: Decentralization in healthcare is about giving more power to local communities and peer groups, especially comes holding doctors accountable. That approach is inherently different from centralized systems, where decisions come from the top down, creating big gaps between those making the rules and those following them. In decentralized healthcare, accountability largely comes from peer review and local medical boards. When doctors make mistakes, their colleagues step in to evaluate their practices and decide on appropriate action. peer-based systems actually foster a culture of accountability and flexibility in decision making though. It's not perfect but it's better. decentralized system also allow for a more thoughtful way to handle errors. Local governance actually creates environments where small mistakes serve as learning opportunities rather than triggers for penalties. Decentralization helps minimize the chance of major critical errors as well Local decision-making allows healtheare providers to respond quickly to specific community needs, which is essential in preventing serious errors that can occur when a single, one-size-fits-all approach is imposed from above like we saw during the shit show that was Covid. There are downsides with DM medicine as well but they're smaller and more manageable

Even if you don't like RFK (there are many individual decisions he's made that I do NOT agree with), you need to understand why the totality of his approach toward public health policy is actually a systematic step in the right direction (particularly in how he envisions the management and oversight of health agencies) by understanding complex systems, decentralization and skin in the game. Talebs anti-fragility is a good parallel here. In fact, the systems he's setting in place will also limit any harm from his own potentially bad decisions long term. None of the evidence based nitwits will get this though because they're too hyper-focused on the minutia with no understanding or appreciation for the second and third order effects. A shift away from centralized, top-down management towards a model where agency operations could be more influenced by individual leadership and less by overarching federal mandates is ALWAYS going to produce better outcomes. Tons of people died during COVID because idiots with no skin in the game had a direct say in how doctors implemented their clinical expertise in patient care. Decentralization isn't a free for all either. Doctors who make bad or poor decisions will have to face the ramifications in front of boards of other doctors and the state

Q: Thoughts on boron and vitamin k2 for absorption of vitamin D and magnesium?

A: Yes. They're necessary co-factors.

Getting enough boron is likely

achievable via the diet for most but some may benefit from supplement, particularly if they're dealing with arthritic conditions (which vitamin K can also be helpful for). Vitamin K is in my list of 'top priority' supplements for most people, and it can dramatically improve ATP production as well. I think most people should be taking the mitolife vitamin K because it's dosed relatively high. So you can split the capsule in half based on your individual needs. I think many can benefit from using it at higher doses for longer periods of time initially. I have a discount code for it in the bio under the mitolife tab. It is more expensive than most vitamin K's, but it constrains higher doses, better sourced, and includes all 3 K's (MK4, mk7 and KI)

Q: If GH is such a good healing agent, why don't you see it prescribed in the US?

A: For the same reason that virtually everything else that works isn't prescribed in the US - our healthcare system is ass and much of what gets approved is determined by lobbyists. I mean ffs. There are groups of individuals actively still lobbying AGAINST stem cell procedures. Type 1 diabetes has been cured now in two experimental trials in Dubai (and one other country I can't remember) by injecting MUSE cells (I believe) and some other gene edited stem cells into the pancreas to regenerate islet cell function. Bio-regulators cure rod cone dystrophy, and Cortexin and cerebrolysin are tremendous for patients following TBI and stroke. All different drugs available in different countries based on different regulatory laws, approval processes, research fund allocation etc.

Q: How would gene shape hair color but not disease

A: Not an equal comparison. A real challenge comes up when we try to pin down what we mean by character traits, for example. It's straightforward to describe someone by their physical features, like your hair or eye color. But it gets trickier when we talk about traits like ‘aggression.’ Just because animals can act aggressively doesn't mean aggression is a character trait in itself. The same goes for humans-just because some people are attracted to the same sex doesn't mean we can label that as a distinct character trait called homosexuality. These are social behaviors shaped by context and environment. The same is true for environment and health seeking behaviors and disease. When we create a character trait and assign it to a specific gene, we fall into the trap of reification- mistaking processes for concrete entities. Sure there are various mutations that can influence skills like reading or memory, even disease susceptibility but that doesn’t mean we can point to a gene and say,

"This is the gene for reading" Even when it comes to physical characteristics, there’s really no solid reason to separate a ‘character’ from the intricate whole that is an organism. Yet this is exactly what geneticists do when they study development. They might find mutations in certain genes that affect things like how the body segments, and then label those genes ‘segmentation genes.’ This creates complications, especially with the assumption that there are multiple genes (regulated and shaped via environment? working together to determine these traits

So yes. Genes DO influence disease susceptibility. But making that jump to 'genes determine the disease [in absence of the environment]' is mistaken. This is true even with what are commonly reffered to as single gene disorders. I always bring up the studies that Dean Bonlie did with the magnetico and MME technology regulating hundreds of genes, as well as some of the benefits seen in patients with cystic fibrosis (a genetic condition) and other difficult to treat disorders. If you took someone with a 'cystic fibrosis' cluster of mutations and put them in an environment where there's higher magnetic flux, would they have the same issues? I think based on that research you could easily conclude that they wouldn’t. I think the same is true for all Neolithic diseases: food, sunlight, M flux - these are all entangled environmental factors that will impact how the genes are expressed. A gene may or may not mean much in a good environment. The genetic engineering paradigm makes a lot more sense when you subtract out ecological influences

Q: Endometriosis options?

A: Systemic enzyme therapy, KPV peptide and really high doses of specialized pro-resolving mediators. Not a cure. But it can be really helpful in managing the issue. Theres some studies on SPM's for directly inhibiting endometrial lesions. Not Medical advice.

Q: Can fixing dysbiosis in the gut improve food intolerances like egg?

A: Yes. Virtually all food intolerances are microbiome related. The lactose example I gave previously highlights this. Even if you don't have the nuclear genes to digest lactose, they can be easily aquired via the bacterial genome. Histamine sensitivity, and a ton of other immune mediated food reactions can also be tempered and eliminated by favorably alteting the composition of resident microbes in your GI.