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Hamilton Morris
Hamilton Morris

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POD 83: Alan Rockefeller talks fungal genetics, taxonomy, and identification

Recorded after a mushroom foray at this year's Mycofest, I sit down with Alan Rockefeller to discuss Psilocybe taxonomy, wood lover's paralysis, the enigma strain, and fungal accumulation of heavy metals.

Alan's website: https://www.mycena.llc/
Jason Slot - https://plantpath.osu.edu/our-people/jason-c-slot
DNA sequencing - https://ohiomushroomsociety.wordpress.com/

Hoosier Mushroom Society - https://hoosiermushrooms.org/index.php?/profile/3-stephen-russell/

Entheogen Genome Project - https://www.entheome.org/

Felix Blei - Simultaneous Production of Psilocybin and a Cocktail of β‐Carboline Monoamine Oxidase Inhibitors in “Magic” Mushrooms - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003923/

Psilocybe Niveo-tropicalis - https://mushroomobserver.org/520177

Alan's Facebook Group - https://www.facebook.com/groups/MushID/

Comments

Doma just did a interview on mycotrophic’s podcast

Phlegm

hello fellow kiwi. ive been fascinated by waeroa but only ever found subs and a few aucklandii.

Eban (Sully)

The intro to this episode was one of my favorites. I always really enjoy your intros and this one was particularly special. Curiosity for and engagement with the natural world is deeply fulfilling. There is infinite complexity and wonder in life’s silent ecosystems.

gossamer

I had wild Psilocybe ovoideocystidiata from PA analyzed in Michigan (first wild Psilocybe to be analyzed in MI, according to the lab): .82% Psilocybin .21 Psilocin ZERO Norbaeocyctin, Baeocystin, Norpsilocin, or Aeruginascin Just thought someone might be interested

Don King

Kiwi Geneticist here. I would love to assemble a p. Waeroa genome.. Very interesting to hear about research being done about this incredible mushroom

Oscar Graham

Yes, please arrange! Email hamiltonsresearch@gmail.com with any info

Hamilton Morris

Im an expert in chemical analysis of natural products if you ever get funding for chemical analysis of mushrooms Alan!

Justin Fischedick

Doma the winner of the first cup was not the person to really isolate tidal wave. He stole the credit from one of his patrons that went by Miggs. I was on the discord when it all went down. Migs grew the sample that won the cup all the way down to the isolation, agar work, and plate transfers.. In 2022 I meet Doma in person when he was touring with the delta 8 CBD expo and asked him if he isolated TW2z He said he was selling B+ strain swabs and tw2 was isolated from his spores since he was the seller of the swab it was his “genetics” he did not mention migs name but did not say anything about growing it or even isolating it. I know Doma is friends with Alan, but I’m not sure the world really knows Doma. To me this was him omitting he was not giving credit to the person who really did the work. That would make for a great episode if you ever want to try and interview the real creator of tidal wave 2 let me know and I will see if I can arrange.

Keith Jackson

Does the download button not work for anyone else? On mobile btw

ogon bio

Cows always have "explosive diarrhea" it's just a result of having multiple stomachs.

Keegan Crocker

I have had allergic reactions to milk caps in my area. When out taking pics one time I had some of the latex on my hand and rubbed my face and it was burning for sometime after that. also i am mushlovegmaing on iNaturalist. Just found out about it last month. gotta start using it.

MushLove Gaming

Sounds good. I didn't realize that the archaic æ spelling was more faithful to the Latin spelling.

Brian

https://mushroomobserver.org/520177 Here’s a link to a much better observation of Psilocybe niveo-tropicalis nom. prov. This one has high quality DSLR photos

Scott Ostuni

Alan, have you heard anything definitive about the toxicity of Podostroma cornu-damae (poison fire coral)? I have heard rumors that some people have been poisoned just by contact with the skin, but I don't know of any actual documented cases of this. Also, it seems to be so toxic that it might not even be safe to taste it. I almost wonder if the poisonings through skin contact were actually caused by contamination of food from contact with skin that was exposed to it. Anyhow, it would be interesting to hear your take on it.

Brian

Looks like it could be Psilocybe cubensis var. aenigma or Psilocybe cubensis f. aenigma

Alan Rockefeller

It would take a lot of Amanita muscaria to do anything to a cow. Not sure exactly how many.

Alan Rockefeller

The Crime Pays but Botany Doesn't interview that Hamilton did was really good.

Alan Rockefeller

Regarding the discussion at about 39 minutes into the recording about naming the new mushroom species "enigma", it comes directly from Latin, which comes from Greek ainigma (ainissesthai, to speak allusively), so the word could be used in a taxonomic name as-is.

Brian

Is the word describing Enigma not "fasciation"? Or perhaps it was a term exclusive to plants hmm

Oli

How did he sound like a dick? I didn’t get that impression.

Ryan Campbell

So mad I missed you Hamilton- I’ve been repping pharmacopeia for the past 4 years of undergrad in central PA

Devan Ghai

The anecdote with the flourescent sap of Chelidonium majus and sanguinarine caught me very off guard, because I had an almost identical experience when inspecting the equally-orange sap of a flower known as Algemone albiflora (Texas Prickly Poppy). I also noticed it contained sanguinarine and remarked the interesting scaffold. Very cool to hear someone had that same experience.

Ivan Mounteer

Wood lovers paralysis really is fascinating. I’ve never seen anyone experience it nor have I experienced it. Someone above mentioned Parkinsons Disease but don’t think it’s related. Patients with PD have very specific and characteristic movement disorders, mostly related to gait and facial and other movements. There is also chemically mediated nicotinic cholinergic paralysis from certain quaternary alkaloids but this might result in a fatal outcome, which apparently does not happen so I doubt this is any part of the mechanism. I bet it is related to the sleep paralysis, a condition that can result from REM sleep interruption in a non-drugged state. Perhaps there is a Wood lovers alkaloid that has the ability to mediate this normal, REM mediated disconnect in the brain’s motor pathway. Anyone have any experience or thoughts on this?

david

Yes, Hamilton interviewed Joey in episode 62.

Brian

My favorite sperger!

avery maynard

This is an interesting example of a GWAS previously done in Neurospora crassa, a similar study in morphological traits of P. cubensis would be fascinating. https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1003669

Josh Jones

In plant genetics how phenotypic variations are correlated to specific locations in a genome is doing population genetic studies assisted by DNA markers. A great way to do it to do a Genome Wide Association Study (GWAS) that scan for single nucleotide polymorphisms that can be correlated to specific phenotypes. It would work well for identifying what area of the genome a trait like albinism or penis envy morphology comes from. It would be a large project as you would need many unique genotypes to compare and a lot of full genome sequences. Hopefully someone can do something like that in the future to look closer into P. cubensis genetics.

Josh Jones

I picked a few lbs or so of Amanita Muscaria var. Formosa or Guessowii near Island Park in Idaho a few years ago Hamilton. I studied up very well with the different variations like the Angel of Death. We were very careful not to pick any white ones that had not turned color into the yellowish/orange color. The thing I noticed the most on the trail we found them on was that a bunch of cows had eaten a ton of the Amanita mushrooms and the best part was that the cows got explosive diarrhea and there was tons of wet shit exploded around and on the trail. So at least the cows knew they were good lmfao. I think its funny that a lot of mammals like to consume psychoactive substances. Do you think they just wanted a meal or do you think they knew that they could get "high"? I love taking Amanita freshly picked I have eaten about a 6 inch cap de-gilled. I made sure to use a knife to pick them so we did not disturb the mycelium however the mushrooms have not come back since unfortunately...

TripOverThis420

I wouldn’t see much benefit in that

Red-Crested Breegull

Great Conversation!

Jordan Jacobs

Your intro kinda made you sound like a dick. Good episode though

Conifer

Thank you so much Hamilton for answering my question on the best known origin of the “enigma” cubensis mutation 🙏🙏

Keith Keblesh

You're looking for inocybe insignis?

Cheminterested

I have smelled very similar scents while walking though the woods in the lowlands of NC where where I have never seen ovoids. I suspect there are flowering plants that produce a very similar smell.

Cheminterested

I have a friend in southern Ohio and he swears he can smell those same smells. He is the one responsible for reporting the spell of Inocybe insignis. Ohio Mushroom DNA Lab has a bounty on this mushroom. If you meet the requirements then I will pay you the bounty. I need to get HPLC on this one.

Ohio Mushroom DNA Lab (Kyle Canan)

You need to go back and listen, they both thought they were interviewing each other and it's fucking hilarious.

Ohio Mushroom DNA Lab (Kyle Canan)

Awesome, you two together is a power house.

Dustin3D

The effects of wood lovers paralysis sound somewhat similar to the symptoms of parkinson where patients are unable to connect the idea of moving their body with psychically doing it. Could there be a link? Perhaps something with the dopaminergic cells in the substantia nigra?

Max van Oldeniel

Would you ever have Paul Staments on your podcast?

Anthony Roman

Wonderful talk! This is the subject of knowledge I need to gain more of. Thank you for sharing. :)

Nathan Reynolds

Definitely missed that one , thanks 😊

alan padgett

He has interviewed Joey before, but I'd love to hear a second one

Cheminterested

Hey. Thanks for mentioning my ovoid smell question. I think I may have asked Alan before on Facebook as well. Would be fascinating to see what some of the terpenes are

Cheminterested

YESSSS next let's get tony from crime pays but botany doesn't

alan padgett

This talk is GOLD

Ethan A.T. Miller

Hamilton, I know spots in nature for Psilocybe ovoideocystidiata on the Ohio border. I can take you next year. Or talk to you over email and give coordinates. But living in PA you could easily find them by searching iNat sometimes.

Ohio Mushroom DNA Lab (Kyle Canan)

The Ohio Mushroom Society article was written by myself, however I have rebranded my sequencing project from Love Our Land to my permanent brand the Ohio Mushroom DNA Lab. I can be found here: https://www.facebook.com/kyle.canan.1/

Ohio Mushroom DNA Lab (Kyle Canan)

This is the collab of the century

Kyra Frank

i love his public center in nyc

Eloi Jeshua Ramirez

I watched it happen now I get to listen!

Ohio Mushroom DNA Lab (Kyle Canan)


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