PODCAST 38: Ethnobotanical investigations with Dr. Mark Plotkin

silly boulder he will never want you

🌺ily🥀

put it this way I'm the only chief's granddaughter that wants to talk to you on the phone https://on.soundcloud.com/RLFWZ

swatches

Great intro Mr. Morris

giticzb

Hamilton mentions a paper about traditional use of psilocybin containing mushrooms in Uganda. I'd love to read that, but I'm not having any luck locating it. Any hints would be much appreciated. :-)

Tom B

If you're not familiar and looking for similar opportunities, there's actually an organization dedicated to matching adventure athletes with research projects: https://www.adventurescience.com

Hank Raizen

Very interesting. For the last seven months I've gone climbing twice a week and have become very into it. I hangboard train every day. I only go bouldering in gyms at this point (haven't been able to do anything over V4) but I never considered an intersection between ethnobotany and climbing, that's some new motivation!

Hamilton Morris

Cool to see this pop up. Some years ago I tried to organize an expedition to Chiribiquete (I was a professional climber at the time, and the park has some otherworldly rock formations). I reached out to Plotkin asking it he would have any interest in the unique access to local flora that we as climbers could provide. He wasn’t terribly interested, and the trip never happened, but I’m still curious what botanical secrets those massive cliffs might be hiding.

Mason Earle

Such an interesting plant, I have been told tat some herbalists at rainbow gatherings have used it to bring people down from bad trips, and I once experimented with it on a wingnut friend (consensually, and while he was enjoying his trip) and he said it dramatically changed his visuals and then he fell asleep about an hour later. I have not been able to find any published studies on what chemicals it contains. It's fascinating. I worry about it getting overharvested tho.

Eric Daugherty

" Hanging with the home boys"

Hi Hamilton! Thank you so much for this interview! It was very enlightening! I’m curious about your findings with ghost pipe. This is a plant I have been very passionate learning about, and have made my own extracts from sustainability harvested material, and it’s very hard to find any info on the composition. Of this herb, but have found it fascinating and healing. You mentioned that there are like 40 different alkaloids, and would like to know if you know where to find a list of these alkaloids that are present in the samples you’ve collected, and if you have any approximate quantities of these samples. Thank you so much! Your work is inspiring as always.

Maybe give the indigenous people stock in the corp that isnt making money yet, but will 'someday'. Or found a 5013c with a local mission, and give some stock to that.

Hamilton, Your work both technical & informative is so very important to me. I know this particular type of time sink could feel silly & even counter productive, but you are my deep root to one of my favorite topics of research. I hope you continue these talks, both semi personal & industry related. You provide some of the only “content” I cannot get enough of. Stay strong, everyone seems so damn amped up in the world. I just wanted to say thank you, I think of you often.

Anon

Holy shit thanks man, I figured maybe they had isolated 4-ho-3 indole acetic acid also from pilocybe and that was the inspiration but this is great info!!

It was definitely inspired by psilocin, it appears to have been synthesized by Franz Troxler and Albert Hofmann in 1966 at Sandoz in Switzerland. I saw something online (there was no citation) that said the original synthesis was done with 4-hydroxyindole that was left over in Hofmann's lab after his work on psilocin, psilocybin, 4-HO-DET, etc. The original patent citation is: Sandoz - NL601040, 1966 [Chem.Abstr., vol. 66, # 18669]

Hamilton Morris

Who was the first person to synthesize pindolol? Someone please help!! There seems to be a dearth of information on the origin, although it is an ether of 4-HO indole and possibly Plotkin is correct that is was inspired by psilocin.

Man please let me know what I can do to help advocate for these drugs to stay off the sched 1

Mitchell

Dude this cacao expert keeps on flaking on me lmao the first time his daughter was sick and Friday he was sick. Seems like something you would deal with. Tryna link up w ppl

Devan Ghai

Love it, need to figure out the poping mic situation. I think you need to step back or get a pop filter.