Dopamine is a well known neurotransmitter often associated with the brain's reward system, and has also been srudied for its role in controlling skeletal muscle mass and force production. Some papers have shown that the activation of dopamine receptors, particularly dopamine 1 and dopamine 5 receptors, directly influence skeletal muscle physiology in some pretty cool ways.
One key mechanism through which dopamine affects skeletal muscle is by increasing muscle mass and force product...
2024-08-04 15:19:56 +0000 UTC
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Watch the introductory video for the protocol bellow
https://youtu.be/vwKcgt7_8RA?si=023qOa1HjcNXC850
We all know progressive overload is important. But after a certain point it becomes challenging. The micro-loading protocol will help you realize that it’s actually fairly easy to accomplish things in training that some believe are impossible unless you have freak genetics...
2024-07-31 20:42:30 +0000 UTC
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Video link
https://youtu.be/00eZRneJicM?si=FE-vG5pcLncZsEOD
The vjdeo above talks about how to use shockwave therapy for MSK pain and various injuries. Shockwave is probably the second best ‘passive’ treatment modality aside from PEMF for treating complex pain and injuries.
A brief overview on shockwave therapy
Shockwave therapy has been shown ...
2024-07-25 22:48:07 +0000 UTC
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This is particularly important post/info to know if you have a diagnosed connective tissue disorder (or you know you have mutations in genetive tissue genes) and are struggling to eradicated something like Candida/yeast
6 years ago, I made the connection between connective tissue disorders like EDS (ehlers danlos), mitral valve prolapse, and reoccurent, systemic Candida and fungal infections ancedotelly. This was after analyzing over 20 clients who had done an iridology exam. Iridology...
2024-07-21 17:24:08 +0000 UTC
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A ‘panacea’ supplement comparable to PEDS for power output? Sounds too good to be true
5-amino-1MQ is a small, membrane permeable molecule (so not exactly a peptide although it’s often lumped into that category) that has gained a lot of attention for potential benefits in within the context of muscle growth, fat metabolism and (most importantly in my opinion) dramatically improving muscle strength and power output. Some have even claimed it helped them to shave .3...
2024-07-21 13:45:52 +0000 UTC
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The nutritional shake I drink everyday has been a part of my diet for the past 6-7 years. One of the reasons I like having a liquid meal thrown into a diet is because it’s particularly easy to digest and it’s easy way to conviently cram a lot of good nutrition in there.
There’s also some good data on replacing meals with 1 or 2 liquid meals, particularly for individuals with SIBO and other gastrointestinal issues.
While the shake is obviously blended, it’s still a good i...
2024-07-19 17:00:33 +0000 UTC
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Fungal infections on the skin, such as those caused by Candida species, can be interconnected with gut health, and the relationship between skin and gut health is increasingly understood to be bidirectional rather than unidirectional. While it's well known that gut dysbiosis (an imbalance in gut microbiota) can influence skin health, there is growing evidence to suggest that skin conditions can also impact gut health.
The skin and gut are both heavily involved in the body's i...
2024-07-16 16:40:53 +0000 UTC
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Optimizing natural testosterone and hormone production requires a multi-faceted approach that addresses various pillars of good health. While this article cannot possibly encompass all the relevant steps involved, we will cover some basic lifestyle recommendations in addition to some supplemental strategies. It's important to note that the testosterone equation is influenced just as much by how you choose to live and what you avoid as it is by the supplements you take and the foods you eat. W...
2024-07-13 15:21:13 +0000 UTC
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When we think about micro organisms like parasites and bad bacteria, we can clearly see examples of these ‘bad bugs’ altering human behavior in negative ways.
In a pathological context, we know that parasites like toxoplasma gondii can infect many warm-blooded animals, including cats and humans. In cats, which are its definitive hosts, it completes its sexual reproduction cycle. When it infects intermediate hosts, such as rodents, the parasite manipulates their behavior...
2024-07-10 13:42:09 +0000 UTC
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Q: Should choline and citrulline be avoided due to heart disease risk
A:
I think that's a little over blown. There are definitely associations with certain nutrients and the development and progression of certain disease. So there's nuance that needs to be added depending on the health status of the individual. But that's kind of what I'm getting at — the health status of the individual is largely what determines that and how things get used. N...
2024-07-09 15:44:34 +0000 UTC
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Q: Thoughts on idea that leaky skin driving disease vs a reflection of health internally
A:
Everything is interdependent and bi directional. skin issues can be a reflection of health 'on the inside' like you mentioned, but they can also feed back into the problem and drive those changes as well. That is a credible idea. dermatological conditions will contribute to systemic low-grade inflammation and immune dysregulation. Remember, the skin is a l...
2024-07-04 15:27:59 +0000 UTC
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Similar to other infections like Candida and SIBO, H pylori is highly prevelant. It’s estimated that around 50% of the adult US population has an opportunistic overgrowth of H pylori in the gut.
H pylori is a type of bacteria that primarily infects the stomach. It is known to be a major cause of peptic ulcers and is associated with several gastrointestinal conditions, including gastritis, leaky gut, endotoximia and gastric cancers as well
increased intestinal permeability (wher...
2024-07-04 14:15:28 +0000 UTC
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To effectively shift your circadian clock while traveling, it’s crucial to establish a strong diurnal rhythm before departure. By doing this, your body will rely on familiar cues to modulate sleep-wake cycles more effectively, in combination with the adjuncts listed below. If your circadian clock is already dysregulated before leaving, these strategies will not be as effective
We don't need to spend too much time on this, but the most important factors in setting your circadian rhythm...
2024-06-30 19:27:56 +0000 UTC
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1. Press the panel into your skin
When the red light panel is pressed closer to the skin, several physical principles come into play that enhance the effectiveness of the therapy:
Irradiance is the power of electromagnetic radiation per unit area (measured in mW/cm²). By reducing the distance between the light source and the skin, the irradiance increases, meaning more energy is delivered to the skin in a shorter period. Light penetration into tissues follows the principles of...
2024-06-28 16:30:51 +0000 UTC
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Article at a glance (TLDR)
1. Stoping inflammation with advil or prescription anti-inflammatories is bad because it blunts the arm of the inflammatory cascade necessary for healing.
2. Supplements like SPM’s and PEA (which can both be supplemented) are involved in the resolution phase of the inflammatory process: the resolution phase involves promoting authentic healing and clearing out debry, waste and cellular dama...
2024-06-25 15:31:08 +0000 UTC
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TLDR/ Key take aways at a glance
1. Cold exposure potentially has theoretical benefits that go far beyond reducing inflammation and or a temporary dopamine boost. Particularly the ability to enhance cellular and metabolic processes related to increased cellular energy production and biophoton emession (creating light from within the body)
2. Embrace the winter. Very few people ever experience a true winter. Take your shirt off and get outside if you ca...
2024-06-22 19:49:32 +0000 UTC
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I want you to think of manual therapy as the recovery of localized, dynamic spaciousness within a tissue or structure via an applied external force — wait what?
When we train, we apply local and systemic forces to the body. Similarly, manual therapy also exerts an external ‘force’ on the tissue, which the body will still have to respond ‘reflexively’ to. In this sense, we shouldn’t think about manual therapy as being ‘passive’ and strength training as being ‘activeâ€...
2024-06-19 21:34:13 +0000 UTC
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For those who aren't familiar with my journey with partial hearing loss, I'll briefly share it here.
I experienced several incidents—some chronic, some acute—that led to 30-40% hearing loss during high school and late into college. Specifically, I lost about 25% of my hearing in my right ear and 40% in my left ear.
I did just about everything imaginable that could contribute to hearing loss. I frequently attended loud concerts, often standing and or being positioned...
2024-06-16 16:07:03 +0000 UTC
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Ehlers danlos syndrome is agroup of inherited conditions that affect the bodies ability to produce sufficent levels of collagen. Collagen is important for connective tissue, which provides support in skin, tendons, ligaments, blood vessels, internal organs, and bones. Symptoms of EDS can vary but typically include an increased range of joint movement (ioint hypermobility), stretchy or fragile skin that bruises easily, joint pain, and an increases risk of things like aortic dissection, prola...
2024-06-14 23:10:28 +0000 UTC
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Q: Any reason glycine makes me more irritable instead of sleepy
A:
Yes. A lot of people can have paradoxical reactions to glycine. It's a co-agonist (I believe) of the NMDA receptor. which is a subtype of glutamate receptor. So when glycine levels are elevated it can potentiate the excitatory effects of glutamate on the receptors can cause an increase calcium influx and excitotoxicity. But then again like I mentioned in the last story, people can...
2024-06-14 14:49:44 +0000 UTC
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In a study titled 'Induction of autologous mesenchymal stem cells in the bone marrow by low-level laser therapy has profound beneficial effects on the infarcted rat heart' rats were given an experimentally induced heart attack, then researchers exposed the rats tibias (an area with lots of bone marrow) to 660nm red light and observed some surprisingly profound effects
"Infarct size and ventricular dilatation were significantly reduced (76% and 75%, respectively)'
2024-06-14 00:32:20 +0000 UTC
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MRET water was invented by Dr. Igor J. Smirnov, a Russian scientist who conducted research in the field of biophysics and biochemistry related to water and its structure. The technology behind MRET water was developed as a result of studying the effects of electromagnetic fields on biological systems and water
The connection to Chernobyl in relation to MRET water is not directly related to its discovery like many have claimed. I’m sure everyone has heard the eye rolling story of the ...
2024-06-11 22:29:57 +0000 UTC
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Saturated fats have long been a contentious subject of heated debate i n nutritional science and public health discourse. Historically, they were broadly categorized as detrimental to health, particularly concerning cardiovascular disease. However, new research indicates that not all saturated fats exert the same effects on the human body.
The role of carbon chain length
The molecular structure of saturated fats, specifically the length of their carbon chains, significantly inf...
2024-06-10 01:22:36 +0000 UTC
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Neuropeptides, which are peptides active within the central nervous system, are increasingly recognized as key players in the development and manifestation of depression. Studies have indicated that peptides such as vasopressin, galanin, and neuropeptide Y play a crucial role in the regulation of monoamine receptor activity. This suggests that the issue with depression may not be as simple as a ‘chemical imbalance but rather a complex issue of improper chemical regulation and signaling mech...
2024-06-07 22:26:53 +0000 UTC
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I’m going to be re-updating the COVID-19 vaccine protocol here with some new data and information that’s recently come out. This is written not just for the 'vaccine injured', but also for those have been vaccinated but don't have symptoms as well as patients with long COVID.
There will be some considerable overlap here as the symptoms of long COVID and vaccine related injuries have similar symptoms and underlying spike protein and immune dysregulation centered etiologies...
2024-06-05 20:50:40 +0000 UTC
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I’m going to be re-updating the COVID-19 vaccine protocol here with some new data and information that’s recently come out. This is written not just for the 'vaccine injured', but also for those have been vaccinated but don't have symptoms as well as patients with long COVID.
There will be some considerable overlap here as the symptoms of long COVID and vaccine related injuries have similar symptoms and underlying spike protein and immune dysregulation centered etiologies...
2024-06-05 15:08:48 +0000 UTC
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Q: Best things for anxiety and depression overall? Like if someone has tried everything
A: Psychobiotics, FMT (or other microbiome interventions) neurofeedback, vagus nerve injections, Stallate ganglion block, neurofeedback, Fischer Wallace neurostim, TMS, electrical vagus nerve stimulation, psychedelic assisted forms of therapy, good meditative practice, PE-22-28, Semax, photobiomodulation.
Q: Best budget supplements for joint health?
2024-06-03 18:10:27 +0000 UTC
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Q: Lactoferrin for high iron/ferritin and general immune support? I've been taking 250 mg daily
A: Lactoferrin can be useful for that yes. Currcumin, Quercitin, and green tea are also good iron chelators. For that reason, those also might be something to avoid for anyone reading this who's anemic and consistently finding that they feel worse taking things that are supposed to be 'good' for them. @drtylerpanzner discussed this today on the podcast we jus...
2024-06-02 23:57:49 +0000 UTC
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Carbon dioxide therapy (not to be confused with carb MONOXIDE which is lethal) is a powerful therapy that has been used in Europe in hot springs for centuries.
C02 therapy (in its many different forms) is one of the few ‘therapeutic’ modalities (along with PEMF) that I’ve found to be particularly effective at exercise performance and recovery. CO2 baths in particu...
2024-06-02 16:52:42 +0000 UTC
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This is going to be the first installment of many book reviews. It’s a great opportunity to get a glimpse into what I’m currently reading. I also want this to be almost a long format version of some of —what I would consider to be — my best content posted on instagram. I’ll be reviewing the ideas in the book, but also extrapolating out on them with some of my own ideas and concepts for reference.
Mind and Tissue by Ray Peat
Ray Peat's book ...
2024-05-29 16:07:18 +0000 UTC
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